This volume presents the proceedings of an interdisciplinary workshop at Braunschweig University of Technology in a collection of English and German articles (English summaries are provided for all German articles). Focusing on biotechnology, experts from biology, biotechnology, ethics, philosophy, theology, education, and social sciences investigated how metaphors shape the language of life science. The authors examined conceptual, absolute, and hidden metaphors (e.g., “genetic scissors,” “genetic code,” “antibodies,” and “life”) in molecular biology and biotechnology. By exploring their roles in describing phenomena, guiding research, and influencing public perceptions, the authors investigate how metaphors generate and transform knowledge, affect views of life and therapy, and inspire innovation. This volume integrates systematic metaphor analysis with ethical, philosophical, and pedagogical perspectives on the significance of metaphors in biotechnology research and dissemination. Special attention was paid to metaphors’ role in public communication, potentially determining acceptance or rejection of biotechnological advances. Ultimately, the workshop underscored how metaphors influence scientific progress in multiple ways and therefore require critical reflection.