This book contains the revised and extended versions of selected papers from the 15th International Conference on Agents and Artificial Intelligence, ICAART 2023, held in Lisbon, Portugal, during February 22–24, 2023. The 23 full papers included in this book were carefully reviewed and selected from 306 submissions. The conference was organized in 2 tracks as follows: One track focuses on Agents, Multi-Agent Systems and Software Platforms, Distributed Problem Solving and Distributed AI in general. The other track focuses mainly on Artificial Intelligence, Knowledge Representation, Planning, Learning, Scheduling, Perception Reactive AI Systems, and Evolutionary Computing and other topics related to Intelligent Systems and Computational Intelligence.