This book aims to overview the variety of nanographenes. Their diverse morphologies, mostly stemming from their structural defects, different approaches of synthesis, their singular chiroptical and photophysical properties and potential applications are covered in this book. Includes both top-down approach where nanographenes are obtained from graphite by fragmentation of pristine graphene by chemical methods, leading to non-homogeneous NGs (flakes) without control of their size and shape and bottom down approach is using standard synthetic chemical protocols resulting in homogeneous and well-defined discrete molecules with a full control on their size and shape.